over 70's extended isolation

[exdos]

NHS Blood and Transplant have started to collect plasma from donors who have recovered from C-19 for use in a trial treating patients seriously ill with it. There is quite a lot of hope that it will be successful.

If anybody on here feels so inclined they are looking for more donors - currently 6,500 have signed up to donate. If you are between 17 and 66, over 50kg, not previously transfused and live near one of their 23 donor centres they would like to hear from you.

https://www.nhsbt.nhs.uk/how-you-can-help/convalescent-plasma-clinical-trial/

The process takes around 40 minutes. As a platelet donor of many years standing (a similar process that takes around 60 minutes) I can tell you it doesn't hurt and is completely safe.

I'm aware of this modality which was first trialled in 1892 with Diptheria and was attempted during the Spanish Flu pandemic. In the case of Dengue Virus infection, apparently it makes the condition worse as it causes the virus to replicate!

Bearing in mind that there are many dozens of C-19 vaccines being developed, it seems to me that the odds are more in favour of at least one vaccine being approved before plasma therapy might be proven and approved.

I know most people think the US President is totally mad, but have a read of this article about how donated whole blood and blood products are treated before transfusion to see that both "disinfectants" and UV radiation are used. https://watermark.silverchair.com/l...giRkWTM11qROs1dOQJpTBvVm84u80jMvm2BEDTYCsGmwM


Also take a look at this paper about UV blood therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122858/

 

[BeeEmm]

I know most people think the US President is totally mad, but have a read of this article about how donated whole blood and blood products are treated before transfusion to see that both "disinfectants" and UV radiation are used. https://watermark.silverchair.com/labme ... EDTYCsGmwM

Also take a look at this paper about UV blood therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122858/

Na! no thanks.

 

[ronk]

We’ve just got to hope the boffins come up with a vaccine soon - however I think a treatment is probably the most likely at this time.

Why do you think a treatment for C-19 is more likely than a vaccine? What's the evidence for that point of view?

I think your question has been responded to more eloquently and in more depth than I would have been capable of!
My opinion was swayed merely by news coverage.
Until the boffins sort something out I’m keeping a low profile and trying to remain optimistic.

 

[Vornwend]

NHS Blood and Transplant have started to collect plasma from donors who have recovered from C-19 for use in a trial treating patients seriously ill with it. There is quite a lot of hope that it will be successful.

If anybody on here feels so inclined they are looking for more donors - currently 6,500 have signed up to donate. If you are between 17 and 66, over 50kg, not previously transfused and live near one of their 23 donor centres they would like to hear from you.

https://www.nhsbt.nhs.uk/how-you-can-help/convalescent-plasma-clinical-trial/

The process takes around 40 minutes. As a platelet donor of many years standing (a similar process that takes around 60 minutes) I can tell you it doesn't hurt and is completely safe.

I'm aware of this modality which was first trialled in 1892 with Diptheria and was attempted during the Spanish Flu pandemic. In the case of Dengue Virus infection, apparently it makes the condition worse as it causes the virus to replicate!

Bearing in mind that there are many dozens of C-19 vaccines being developed, it seems to me that the odds are more in favour of at least one vaccine being approved before plasma therapy might be proven and approved.

I know most people think the US President is totally mad, but have a read of this article about how donated whole blood and blood products are treated before transfusion to see that both "disinfectants" and UV radiation are used. https://watermark.silverchair.com/l...giRkWTM11qROs1dOQJpTBvVm84u80jMvm2BEDTYCsGmwM


Also take a look at this paper about UV blood therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122858/

I couldn't get the first link to work but an interesting article on UBI. Not my area of expertise but I think I heard that C-19 is not viable in blood? - presumably why blood transfusion is not impacted by it. Funnily enough I used to know one of the researchers listed (Pamphilon) as we both worked for NHSBT.

I guess time will tell whether or not treatments emerge before vaccines. I think NHSBT are quite hopeful as evidenced by plans to get to 10,000 donations per week by June which would be a c40% increase in the usual number of donations and suggests they think approval would be quite quick. Fingers crossed either way!

 

[exdos]

I couldn't get the first link to work but an interesting article on UBI. Not my area of expertise but I think I heard that C-19 is not viable in blood? - presumably why blood transfusion is not impacted by it. Funnily enough I used to know one of the researchers listed (Pamphilon) as we both worked for NHSBT.

I guess time will tell whether or not treatments emerge before vaccines. I think NHSBT are quite hopeful as evidenced by plans to get to 10,000 donations per week by June which would be a c40% increase in the usual number of donations and suggests they think approval would be quite quick. Fingers crossed either way!

I thought both articles were worth reading and sorry the first link is difficult to access. You can find it by searching for the paper entitled "Strategies for Inactivation of Viral and Bacterial Contaminants in Blood and Blood Components" found on the website at academic.oup.com. For those who can be bothered to read them, it rather disarms the knee-jerk criticism of Trump's comments, but then again, why spoil blind prejudice with information? :evil:

Personally, I care not which treatment and/or vaccine comes to our rescue I just hope that many highly effective and easy to produce cures can be delivered en masse sometime soon.